Adding ACTIMMUNE® to your treatment
See how ACTIMMUNE® (Interferon gamma-1b) may help your patients with CGD.
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ACTIMMUNE®, an immunomodulatory therapy, helps reduce the frequency and severity of serious infections* in patients with chronic granulomatous disease (CGD).
64%
reduction in the total number and rate of serious infections, including recurrent infections (P < .0001)
67%
reduction in relative risk of serious infections for patients receiving ACTIMMUNE® (P = .0006)
67%
fewer inpatient hospitalization days (P = .02)
As part of a combination treatment regimen along with prophylaxis therapy that includes antibiotics and antifungals, ACTIMMUNE® is recommended by the3-5:
†This does not include all options for managing CGD.
*Serious infection is defined as a clinical event requiring both hospitalization and intravenous antibiotics.
References: 1. ACTIMMUNE® (Interferon gamma-1b) [prescribing information] Horizon. 2. The International Chronic Granulomatous Disease Cooperative Study Group. A controlled trial of interferon gamma to prevent infection in chronic granulomatous disease. N Engl J Med. 1991;324(8):509-516. 3. Bonilla FA, Khan DA, Ballas ZK, et al. Practice parameter for the diagnosis and management of primary immunodeficiency. J Allergy Clin Immunol. 2015;136(5):1186-1205.e1-e78. 4. Leiding JW, Malech HL, Holland SM. Chronic granulomatous disease. Clinical Focus on Primary Immunodeficiencies. 2013;15:1-9. 5. Immune Deficiency Foundation. Diagnostic & Clinical Care Guidelines for Primary Immunodeficiency Diseases. 3rd ed. Towson, MD: Immune Deficiency Foundation; 2015. 6. Gallin JI, Alling DW, Malech HL, et al. Itraconazole to prevent fungal infections in chronic granulomatous disease. N Engl J Med. 2003;348(24):2416-2422. 7. Thomsen IP, Smith MA, Holland SM, Creech CB. A comprehensive approach to the management of children and adults with chronic granulomatous disease. J Allergy Clin Immunol Pract. 2016;4(6):1082-1088.
ACTIMMUNE® (Interferon gamma-1b) is indicated:
ACTIMMUNE® (Interferon gamma-1b) is indicated: